It is a cell-mediated hypersensitivity which is also called delayed hypersensitivity. examples are- 1)contact hypersensitivity- plastic food bowls or poison ivy in humans 2)Granulomatous reaction to mycobacteria, coccidiosis, Histoplasma, Blastomyces. 3)lymphocytic choriomeningitis(hamsters, mice) 4)old dog encephalitis( canine distemper) 5) autoimmune thyroiditis ( also has type 2 component too) 6) keratitis sicca