Epidemiology : sheep-pox is a highly contagious disease. It causes a mortality of 20 to 50 per cent in animals below the age of 6 months, and causes damage to the wool and skin in adults. Of the pock diseases, sheep-pox ranks only second to human small-pox in virulence. The disease is transmissible to in-contact goats but not to other species of animals. It, however, spreads slowly. Symptoms : The disease in characterized by high fever, and symptoms of pneumonia and acute enteritis. Skin lesions appear particularly in parts free from wool, notably around the eyes, inner side of the thigh, udder and under surface of the tail. The internal organs such as trachea, lungs, kidneys and intestines are also affected. The disease results in emaciation and, as already mentioned, frequent deaths of affected animals. Treatment, prevention and control : The diseased animal should be treated with palliatives. In the young ones nursing is more important than medication. The infected litter should be burnt and the bedding changed every day. Affected animals should be kept on soft diet. The ulcers on the skin should be washed with potassium permanganate lotion and dusted with boric acid; strict hygienic measures should be adopted. Preventive measures and treatment (ethnovet): External application of paste prepared by grinding neem leaves, tulsi leaves each 100 gm and turmeric powder- 50gm sprinkled with sufficient water. Continue for 3 to 5 days. Administer orally the same mixture by diluting with water.